Description

MOTS-c is a mitochondrial derived peptide encoded within the mitochondrial 12S rRNA region and consisting of 16 amino acids (MRWQEMGYIFYPRKLR). It has been used in experimental systems as a tool to study cellular bioenergetics and stress responsive signaling, including nuclear associated transcriptional responses reported under certain conditions. MOTS-c is commonly used in preclinical research exploring mitochondrial nuclear communication and metabolic signaling pathways in cell and animal models.

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